Just keep swimming

Holiday bundles, originally uploaded by bbmowery.

It's crunch time here in handmade central, and perhaps in your neck of Santa's workshop as well. I'm making a final trip to the post office this morning with one package for family in the northwest (hope it makes it in time!) and one for The Boy. The mitts and hat will be going for a nice soak tonight. While they are drying I will be conducting questionable activities on my home computer. I drew ornaments on a bunch of paper cd cases, and I fully intend to burn mixes of children's music for our smallish friends. And I don't think anyone can convince me that this is wrong. Except maybe the police.

(Aside: The Violent Femmes said it best, "You were born too soon / I was born too late..." Well, something like that. I was definitely born at the wrong time. I was raised on homemade mix tapes and in college during the pre-Napster file sharing boom. My roommate had thousands of songs on her computer, downloaded for free. Now all the newer cds make it difficult to copy songs to your iPod and impossible to copy to a cd. My magic 8 ball says that next they will make it illegal to sell a used cd when you are tired of it--you will have to return it to the artist. Somebody get Vanilla Ice on the phone because I would like to deliver that one personally.)



The choir had their Christmas party on Monday night at the Dune's Manor Hotel, and I crashed it. I sang with them for two years and miss it very much. Coincidentally, I quit at the same time Aunt Julie retired as music director at the church. Chet had some big shoes to fill. He's done a great job, though, and I hurried to Ocean Pines on Sunday morning to hear the cantata. I was more than a little jealous. So Joyce snuck me into the Christmas party. They always have a gift exchange that spirals into lawlessness. Everyone's total lack of regard for the rules makes it so fun. Unfortunately, I was laughing so hard, I only remembered to take a couple pictures. This photo of Alan made him laugh.

Somehow I got Larry and Alan telling stories about growing up in DC. Warning: if you are over age 65, prolonged exposure to Barb may result in you divulging stories of your wicked youth and childhood that you never intended to tell. It loves to happen. I'm not sure why I have this effect on folks, but I enjoy it tremendously. Jessie's grandma told me where she went "parking" with Jessie's grandpa when they were dating. He bought a yellow car because it was her favorite color. But it was too conspicuous on lover's lane--so she made him sell it. A couple summers ago, Larry told me stories all day at Arts Alive. He was starting in on another, "Back when I was in the Army, we all took showers together....," when he trailed off and looked straight at me. Suddenly remembering his audience. "Why am I telling you this story?" And it was over. I guess that one was a little too racy.

Back to the choir party, the gift exchange was in full swing. You never know what the hot item will be from year to year. One time several ministers kept stealing a bottle of wine from each other. But this year the gifts to covet were the tins of gourmet popcorn, the assorted summer sausages, the boxes of chocolate, and two identical stuffed Santa's. These went round and round many times, until it was hard to remember who had what.

And of course there is always a dud floating through the crowd. One year it was a single jingle bell on a cord. This year someone brought an electronic pill reminder and organizer to the exchange, and Jack unfortunately chose that package. His dinner companions teased that it was for birth control--which he declared was 30 years too late. Someone else suggested it was for viagra.

I drew 53, pretty high in the food chain. When my turn came, I strolled around the ballroom twiddling my fingers like a villain. I walked dangerously close to the popcorn, the stuffed Santa, the sausages...then suddenly dove and stole the pill box from Jack. He cheered! People at my table looked at me like I was crazy, so I said, "Birth control plus cialis sounded like a fun weekend." And they roared. Apparently, I'm the class clown for life. All I could think about, though, was that it would suck for my friend who lost his wife 2 years ago to have to take home a pill organizer for Christmas. So I was really happy when Jack chose another gift, and it was chocolate truffles.

Anyone need an electronic pill box?

kinase inhibitor drugs | Tasocitinib

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Tioguanine (Lanvis®)

Tioguanine (Lanvis®)

Tioguanine (sometimes spelt thioguanine and pronounced thigh-o-gwah-neen) is a chemotherapy drug that is given as a treatment for some types of cancer. It is most usually used to treat leukaemia. This information describes tioguanine, how it is given and some of its possible side effects. It should ideally be read with our general information about chemotherapy and about your type of leukaemia or cancer.

If you have any further questions you can ask your doctor or nurse at the hospital where you are having your treatment, or speak to one of our cancer support service nurses.

• What tioguanine looks like
• How it is given
• Possible side effects
• Less common side effects
• Additional information
• Things to remember about tioguanine tablets

What tioguanine looks like

Tioguanine is available as 40mg yellow order cialis.

How it is given

The cheap cialis should be swallowed whole with plenty of water on an empty stomach.

Possible side effects

Each person's reaction to chemotherapy is different. Some people have very few side effects, while others may experience more. The side effects described in this information will not affect everyone who is given tioguanine, and may be different if you are having more than one chemotherapy drug.

We have outlined the most common and less common side effects, so that you can be aware of them if they occur. However, we have not included those that are very rare and therefore extremely unlikely to affect you. If you notice any effects which you think may be due to the drug, but which are not listed in this information, please discuss them with your doctor or chemotherapy nurse.

Lowered resistance to infection Tioguanine can reduce the production of white blood cells by the bone marrow, making you more prone to infection. This effect can begin seven days after treatment has been given, and your resistance to infection usually reaches its lowest point 10–14 days after chemotherapy. Your blood cells will then increase steadily and will usually have returned to normal levels before your next cycle of chemotherapy is due.

Contact your doctor or the hospital straightaway if:

• Your temperature goes above 38ºC (100.5ºF)
• You suddenly feel unwell (even with a normal temperature).

You will have a blood test before having more chemotherapy to make sure that your cells have recovered. Occasionally it may be necessary to delay your treatment if the number of blood cells (the blood count) is still low.

Bruising or bleeding Tioguanine can reduce the production of platelets (which help the blood to clot). Let your doctor know if you have any unexplained bruising or bleeding, such as nosebleeds, blood spots or rashes on the skin, and bleeding gums.

Anaemia (low number of red blood cells) While having treatment with tioguanine you may become anaemic. This may make you feel tired and breathless. Let your doctor or nurse know if these effects are a problem.

Tiredness and feeling weak You may feel very tired. It is important to allow yourself plenty of time to rest.

Your liver may be temporarily affected Tioguanine may cause changes in the way that your liver works, though your liver will return to normal when the treatment is finished. This is unlikely to cause you any harm, but your doctor will monitor this carefully. Samples of your blood will be taken from time to time to check your liver is working properly.

Less common side effects

Nausea (feeling sick) and vomiting This is unusual, but if you do feel sick it may begin soon after the treatment is given and can last for a few days. If this occurs, your doctor can now prescribe very effective anti-sickness (anti-emetic) drugs to prevent or greatly reduce nausea and vomiting. If it is not controlled or continues, tell your doctor, who can prescribe other anti-sickness drugs that may be more effective.

Sore mouth and ulcers Your mouth may become sore, or you may notice small ulcers during this treatment. Drinking plenty of fluids and cleaning your teeth regularly and gently with a soft toothbrush can help to reduce the risk of this happening. Tell your nurse or doctor if you do have any of these problems, as special mouthwashes and medicines to prevent or clear any mouth infection can be prescribed.

Taste changes You may notice that your food tastes different. Normal taste will usually come back after the treatment finishes.

Diarrhoea This can usually be easily controlled with medicine, but let your doctor know if it is severe or if it continues. It is important to drink plenty of fluids if you have diarrhoea.

Additional information

Other medicines Some medicines can be harmful to take when you are having chemotherapy. Let your doctor know about any medications you are taking, including non-prescribed drugs such as complementary therapies and herbal drugs.

Fertility Your ability to become pregnant or father a child may be affected by taking this drug. It is important to discuss fertility with your doctor before starting treatment.

Contraception It is not advisable to become pregnant or father a child while taking tioguanine, as the developing foetus may be harmed. It is important to use effective contraception while taking this drug, and for at least a few months afterwards. Again, discuss this with your doctor.

Things to remember about tioguanine tablets

• Store the tablets in their original packaging, at room temperature in a dry place away from direct sunlight.
• It is important to take your tablets at the right times. You must take them as directed by your doctor
• Keep the tablets in a safe place where children cannot reach them, as tioguanine could harm them
• If your doctor decides to stop the treatment, return any remaining tablets to the pharmacist. Do not flush them down the toilet or throw them away
• If you forget to take a tablet do not take a double dose. Let the doctor know and keep to your regular dose schedule
• If you are sick just after taking the tablet let your doctor know as you may need to take another one. Do not take another tablet without first telling your doctor.